Anhong Zhou
Biological Engineering
Professor
Contact Information
Office Location: ENGR 402NPhone: 435-797-2863
Email: anhong.zhou@usu.edu
Additional Information:
Teaching Interests
BENG 30000 Bioinstrumentation; BENG 5910/6910 Introduction to Biosensors
Research Interests
• Molecular and cellular imaging • Cellular biomechanics and biophysics • Single molecule detection and single cell assay of cancer biomarkers • Bio-applications of atomic force microscope and Raman microspectroscopy • Lab-on-a-chip, biosensors, and bioelectronics
Awards
Outstanding Graduate Mentor of the Year 2020, 2020
Department of Biological Engineering
PhD student Wei Zhang, Graduate Research and Creative Opportunities (GRCO) award, 2020
USU School of Graduate Studies
PhD student Wei Zhang, Outstanding PhD Scholar of the Year 2020, 2020
College of Engineering
Undergrad Research Assistant Kade Derrick, EURP award , 2020
College of Engineering
Undergrad Research Assistant Kade Derrick, Outstanding Senior, 2020
College of Engineering
Undergrad Research Assistant Kade Derrick, Outstanding Senior of the Year 2020, 2020
Biological Engineering Department
PhD student Wei Zhang, Outstanding Doctoral Student Researcher of the Year 2019, 2019
Department of Biological Engineering
Undergrad student Kade Derrick, Outstanding Senior of the Year 2019, 2019
Department of Biological Engineering & College of Engineering
3rd Place Graduate Student Poster Competition Award, 2015
2015 Annual Institute of Biological Engineering
2015 AFM Image Contest, 2014
Keysight Technologies (formerly Agilent Technologies AFM division)
Finalist, Faculty Researcher of the Year, Robins Award, 2010
Utah State University
Gardner Junior Faculty Travel Fellowship Award, 2010
USU School of Graduate Studies
Outstanding Graduate Mentor of the Year 2010, 2010
Dept. of Biol. Engineering, USU
Outstanding Researcher of the Year, 2010
College of Engineering, USU
Outstanding Researcher of the Year, 2010
Dept. of Biological Engineering, USU
Featured Research entitled “Solving a Protozoan Problem – USU researcher finds new technology to stop deadly parasite from contaminating water supplies” in “Research Matters” magazine, 2008
Office of the Vice President for Research, USU
Outstanding Researcher of the Year, 2008
Dept. of Biological Engineering
Featured Research in “Creating Tomorrow”, College of Engineering Alumni Magazine, 2007
USU
Outstanding Researcher of the Year, 2007
Dept. of Biological Engineering, USU
Outstanding Undergraduate Research Mentor Award, 2007
Utah State University
Featured Research in “Creating Tomorrow”, College of Engineering Alumni Magazine, 2006
USU
Publications | Abstracts
- Keim, J., Zhang, W., Rutigliano, H., Zhou, A., Polejaeva, I., (2020). Analyzing metabolomic profile of bovine IVF and SCNT embryos through Raman spectroscopy. Reproduction, Fertility and Development
- Li, R., Xiao, L., Suasnavas, E., Issom, C., Larson, D., Rickords, L.F, Zhou, A., (2012). Assessment of Cell Behaviors on TiO2 Nanotube Arrays by Using Atomic Force Microscopy, Raman Spectroscopy, Fluorescence Microscopy. Abstract #2060, Honolulu PRiME 2012, The Electrochemical Society
An asterisk (*) at the end of a publication indicates that it has not been peer-reviewed.
- Chen, Q., McEwen, G.D, Zaveri , N., Karpagavalli, R., Zhou, A., (2011). Corrosion Resistance of Ti6Al4V with Nanostructured TiO2 Coatings: Emerging Nanotechnologies in Dentistry: Materials, Processes, and Applications. Elsevier
- Zhou, A., McEwen, G.D, Tang, M., Wu, Y.Z, (2011). Combined AFM/Raman microspectroscopy for characterization of living cells in near physiological conditions: Microscopy Book Series - Volume # 4: Microscopy: Science, Technology, Applications and Education. *
Publications | Book Chapters
An asterisk (*) at the end of a publication indicates that it has not been peer-reviewed.
Publications | Journal Articles
Academic Journal
- Li, Q., Parchur, A.K, Zhou, A., (2016). In vitro biomechanical properties, fluorescence imaging, surface-enhanced Raman spectroscopy, and photothermal therapy evaluation of luminescent functionalized CaMoO4:Eu@Au hybrid nanorods on human lung adenocarcinoma epithelial cells. Science and Technology of Advanced Materials, 17:1, 346-360.
- Parchur, A.K, Li, Q., Zhou, A., (2016). Near-infrared photothermal therapy of Prussian-blue-functionalized lanthanide-iondoped inorganic/plasmonic multifunctional nanostructures for the selective targeting of HER2-expressing breast cancer cells. Biomater. Sci., 4, 1781-1791.
- Li, Q., Xiao, L., Harihar, S., Welch, D., Vargis, E., Zhou, A., (2015). In vitro evaluation of the role of Breast Cancer Metastasis Suppressor 1 (BRMS1) in breast cancer cells to chemotherapy using a multimodal approach. . Analytical Methods, 10162-10169.
- Zhang, W. , Zhang, H., Williams, S., Zhou, A., (2015). Microfabricated three-electrode on-chip PDMS device with a vibration motor for stripping voltammetric detection of heavy metal ions. , 132, 321–326.
- Xiao, L., Chen, Q., Wu, Y., Qi, X., Zhou, A., (2015). Simultaneous Topographic and Single Molecule Recognition Imaging of Epidermal Growth Factor Receptor (EGFR) on Single Human Breast Cancer Cells. Biochimica et Biophysica Acta – Biomembranes, 1848:10, 1988-1995.
- Li, Q., Suasnavas, E., Heywood, S., Xiao, L., Zhou, A., Isom, S., (2015). Biochemical, biophysical and genetic changes of porcine trophoblast-derived stem-like cells during differentiation as evaluated using Raman microspectroscopy, Atomic force microscopy and quantitative polymerase chain reaction. genesis , The Journal of Genetics and Development , 53:12, 749-761. doi: doi: 10.1002/dvg.22907
- Li, Q., Suasnavas, E., Xiao, L., Heywood, S., Qi, X., Zhou, A., Isom, S., (2015). Label-Free and Non-Invasive Monitoring of Porcine Trophoblast Derived Cells: Differentiation in Serum and Serum-Free Media. Journal of Biophotonics, 8:8, 638-645. doi: doi:10.1002/jbio.201400062
- Fernandez, R., Williams, S., Li, R., Zhou, A., (2015). Gapped-duplex Approach to Label-free DNA Mismatch Detection. 56, 1-5.
- Zhou, A., (2014). Photoelectrocatalytic Degradation of Ofloxacin Using Highly Ordered TiO2Nanotube Arrays. Electrocatalysis, 5:4, 379-386.
- Wu, Y., Sims, R.C, Zhou, A., (2014). AFM resolves effects of ethambutol on nanomechanics and nanostructures of single dividing mycobacteria in real-time. , 16:36, 19156 - 19164 .
- Xiao, L., Harihar, S., Welch, D.R, Zhou, A., (2014). Imaging of epidermal growth factor receptor on single breast cancer cells using surface-enhanced Raman spectroscopy. Analytica Chimica Acta, 843, 73-82.
- Li, R., Zhou, A., Lu, Q., Yang, C., Zhang, J., (2013). In situ Monitoring and Analysis of the Photocatalytic Degradation Process and Mechanism on Recyclable Au NPs-TiO2 NTs Substrate Using Surface-Enhanced Raman Scattering. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 436, 270– 278.
- Xiao, L., Tang, M., Li, Q., Zhou, A., (2013). Non-invasive detection of biomechanical and biochemical responses of human lung cells to short time chemotherapy exposure using AFM and Confocal Raman Spectroscopy. Analytical Methods, 5:4, 874 – 879.
- Wu, Y., McEwen, G.D, Tang, M., Yu, T., Dimmick, J.T, Zhou, A., Gilbertson, T.A, Coulombe, R.A, Stevens, J.R, (2013). Sensing biophysical alterations of human lung epithelial cells (a549) in the context of toxicity effects of diesel exhaust particles. Cell biochemistry and biophysics, 67:3, 1147-56.
- Wu, Y., McEwen, G., Tang, M., Dimmick, J., Gilbertson, T.A, Zhou, A., Coulombe, R.A, Stevens, J.R, (2013). Sensing Biophysical Alterations of Human Lung Cells (A549) in the Context of Toxicity Effects of Diesel Exhaust Particles. , 67:3, 1147-1156. doi: doi: 10.1007/s12013-013-9618-4
- Lin, J., Xu, H., Wu, Y., Tang, M., McEwen, G.D, Liu, P., Hansen, D.R, Gilbertson, T.A, Zhou, A., (2013). Investigation of free fatty acid associated recombinant membrane receptor protein expression in HEK293 cells using raman spectroscopy, calcium imaging, and atomic force microscopy. Analytical Chemistry , 85, 1374-1381.
- McEwen, G.D, Wu, Y., Tang, M.J, Qi, X., Xiao, Z., Baker, S., Yu, T., Gilbertson, T.A, DeWald, D.B, Zhou, A., (2013). Subcellular Spectroscopic Markers, Topography and Nanomechanics of Human Lung Cancer and Breast Cancer Cells Examined by Combined Confocal Raman Microspectroscopy and Atomic Force Microscopy. Analyst, 138, 787-797.
- Lin, J., Xu, H., Wu, Y., Tang, M., McEwen, G.D, Liu, P., Hansen, D.R, Gilbertson, T.A, Zhou, A., (2013). Investigation of Free Fatty Acid Associated Recombinant MembraneReceptor Protein Expression in HEK293 Cells Using Raman Spectroscopy,Calcium Imaging, and Atomic Force Microscopy. ANALYTICAL CHEMISTRY, 85:3, 1374-1381.
- Wu, Y.Z, Yu, T., Gilbertson, T.A, Zhou, A., Xu, H., Nguyen, K.T, (2012). Biophysical Assessment of Single Cell Cytotoxicity: Diesel Exhaust Particle-Treated Human Aortic Endothelial Cells. Plos One, 7:5, doi: 10.1371/journal.pone.0036885
- Tang, M., Li, Q., Xiao, L., Li, Y., Jensen, J.L, Liou, T.G, Zhou, A., (2012). Toxicity effects of short term diesel exhaust particles exposure to human small airway epithelial cells (SAECs) and human lung carcinoma epithelial cells (A549). Toxicology Letters, 215, 181-192.
- Davis, M.L, Mounteer, L.C, Stevens, L.K, Miller, C.D, Zhou, A., (2011). 2D motility tracking of Pseudomonas putida KT2440 in growth phases using video microscopy. Journal of Bioscience and Bioengineering, 111:5, 605-611.
- Zaveri, N., McEwen, G.D, Karpagavalli, R., Zhou, A., (2010). Biocorrosion Studies of TiO2 Nanoparticle Coated Ti-6Al-4V Implant in Simulated Biofluids. Journal of Nanoparticle Research, 10, 1609-1623.
- Wu, Y., McEwen, G.D, Harihar, S., Baker, S.M, DeWald, D.B, Zhou, A., (2010). BRMS1 expression alters the ultrastructural, biomechanical and biochemical properties of MDA-MB-435 human breast carcinoma cells: An AFM and Raman Microspectroscopy Study. Cancer Letters, 293, 82-91.
- Wu, Y., Zhou, A., (2010). Fluctuations in adhesion behavior of dividing/budding mycobacterium sp. (strains JLS, KMS, MCS): an AFM evaluation. Micron, 41, 814-820.
- McEwen, G.D, Wu, Y., Zhou, A., (2010). Probing Nanostructures of Bacterial Extracellular Polymeric Substances (EPS) versus Culture Time by Raman Microspectroscopy and Atomic Force Microscopy. Biopolymers, 93:2, 171-177.
- Wu, Y., McEwen, G.D, Baker, S.M, Yu, T., Gilbertson, T.A, DeWald, D.B, Zhou, A., (2010). Topography, nanomechanics, and cell surface components of cancer cells exploited by combined atomic force microscopy and Raman microspectroscopy. . SPIE Photonics West
- Chen, Y., Sun, R., Zhou, A., (2010). An Improved Hurst Parameter Estimator Based on Fractional Fourier Transform. Telecommunication Systems, 43:3-4, 197 - 206. doi: 10.1007/s11235-009-9207-4
- Sathyapalan, A., Zhou, A., Kar, T., Zhou, F., Su, H., (2009). A novel approach for the design of a highly selective sulfate ion selective electrode. Chemical Communications, 325-327.
- Gardner, R.D, Zhou, A., Zufelt, N.A, (2009). Development of a Microelectrode Array Sensing Platform for Combination Electrochemical and Spectrochemical Aqueous Ion Testing. Sensors and Actuators B, Chemical, 136:1, 177-185.
- McEwen, G.D, Chen, F., Zhou, A., (2009). Immobilization, hybridization, and oxidation of synthetic DNA on gold surface: electron transfer investigated by electrochemistry and scanning tunneling microscopy. Analytica Chimica Acta, 643, 26-37.
- Wu, Y., Zhou, A., (2009). In situ, real-time tracking of cell wall topography and nanomechanics of antimycobacterial drugs treated Mycobacteria JLS using atomic force microscopy. Communications, 45, 7021-7023.
- Chen, F., Zhou, A., Yang, H., (2009). STM lithography on HS-ssDNA SAM modified Au (111) surface. Applied Surface Science, 255, 6832-6839.
- Zou, S., Carey, J.R, Liedo, P., Ingram, D.K, Muller, H.G, Wang, J.L, Yao, F., Yu, B., Zhou, A., (2009). The Prolongevity Effect of Resveratrol Depends on Dietary Composition and Calorie Intake in a Tephritid Fruit Fly. Experimental Gerontology, 44:6-7, 472-476.
- Sheng, H., Sun, H., Mounteer Jr., L.C, Kmetzsch, V.G, Miller, C., Zhou, A., (2009). A Fractional Order Signal Processing (FOSP) Technique for Chemotaxis Quantification Using Video Microscope. Proceedings of the ASME 2009 International Design Engineering Technical Conferences & Computers and Information in Engineering Conference IDETC/CIE 2009
- Sheng, H., Zaveri, N., Zhou, A., (2009). Analysis of Electrochemical Noise (ECN) of TiO2 Nanoparticles coated Ti-6Al-4V in Simulated Biofluids Using Fractional Order Signal Processing (FOSP) Techniques. Proceedings of the ASME 2009 International Design Engineering Technical Conferences & Computers and Information in Engineering Conference IDETC/CIE 2009
- Zhou, A., Zaveri, N., Mahapatra, M., Deceuster, A., Peng, Y., Li, L., (2008). Corrosion resistance of pulsed laser-treated Ti-6Al-4V implant in simulated biofluids. Electrochimica Acta, 53:15, 5022-5032.
- Chen, Y., Zhou, A., Sun, R., Zaveri, N., (2008). Fractional Order Signal Processing of Electrochemical Noises. Journal of Vibration and Control, 14:9-10, 1443-1456. doi: 10.1177/1077546307087438
- Shi, Y., Dou, H., Zhou, A., Chen, Y., (2008). Design and fabrication of a miniaturized electrochemical instrument and its preliminary evaluation. Sensors and Actuators: B, Chemical, 131:2, 516-524. doi: 10.1016/j.snb.2007.12.053
- He, H.J, Pires, R., Zhu, T.N, Zhou, A., Gaigalas, A.K, Zou, S., Wang, L., (2007). A Fluorescence Resonance Energy Transfer Based Method to Detect Nuclear Factor κB Activation. BioTechniques, 43:1, 93-98.
- Karpagavalli, R., Zhou, A., Chellamuthu, P., Nguyen, K., (2007). Corrosion behavior and biocompatibility of nano-structured TiO2 film on Ti6Al4V. Journal of Biomedical Materials Research, Part A, 83:4, 1087-1095.
- Wang, Y., Zhou, A., (2007). Spectroscopic studies on the binding of methylene blue with DNA by means of cyclodextrin supramolecular systems. Journal of Photochemistry Photobiology, Part A, 191:1, 121-127.
- Zhou, A., (2007). An improved Hurst parameter estimator based on fractional Fourier Transform. Proceedings of DETC’07, 2007 ASME Design Engineering Technical Conferences
- Zaveri, N., Sun, R., Zufelt, N., Zhou, A., Chen, Y., (2007). Evaluation of microbially influenced corrosion with electrochemical noise analysis and signal processing. Electrochimica Acta, 52:19, 5795-5807. doi: 10.1016/j.electacta.2007.02.084
- Kriparamanan, R., Aswath, P., Zhou, A., Tang, L., Nguyen, K.T, (2006). Nanotopography: Cellular Responses to Nanostructured Materials. Journal of Nanoscience and Nanotechnology, 6:7, 1-15.
- Zhou, A., Sun, R., Zaveri, N., (2006). Local Analysis of Long Range Dependence Based on Fractional Fourier Transform. SMCals/06, 2006 IEEE Mountain Workshop on Adaptive and Learning Systems
- Khraiche, M.L, Zhou, A., Muthuswamy, J., (2005). Acoustic sensor for monitoring adhesion of neuro-2A cells in real-time. Journal of Neuroscience Methods, 144:1, 1-10.
- Zhou, A., Muthuswamy, J., (2004). Acoustic biosensor for monitoring antibody immobilization and neurotransmitter GABA in real-time. Sensors and Actuators B, Chemical, 101:1-2, 8-19.
- Peng, H., Yin, F., Zhou, A., Yao, S., (2002). Characterization of electrosynthesized poly(o-aminophenol) as a molecular imprinting material for sensor preparation by means of quartz crystal impedance analysis. Analytical Sciences, 35:3, 435-450.
- Zhou, A., Xie, Q., Yao, S., (2001). A defect coefficient – new insight into the responses of piezoelectric quartz crystal in gaseous and liquid phase. Sensors and Actuators A, Physical, 88:3, 227-233.
- He, D., Zhou, A., Wei, W., Nie, L., Yao, S., (2001). A new study of the degradation of hyaluronic acid by hyaluronidase using quartz crystal impedance technique. Talanta, 53:5, 1021-1029.
- Zhang, J., Wei, W., Zhou, A., Yao, S., (2001). A novel investigation of magnetic field effects on the sedimentation of erythrocytes with the series piezoelectric quartz crystal sensor. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 180:1-2, 155-161.
- Cai, Y., Xie, Q., Zhou, A., Zhang, Y., Yao, S., (2001). A piezoelectric quartz crystal impedance study on Cu2+- induced precipitation of bovine serum albumin in aqueous solution. Journal of Biochemical and Biophysical, 47:3, 209-219.
- Zhou, A., (2001). Application of double-impedance system and cyclic voltammetry to study the adsorption of fullerols (C60(OH)n) on biological peptide-adsorbed gold electrode. Biomaterials, 22:18, 2515-2524.
- He, D., Chen, F., Zhou, A., Nie, L., Yao, S., (2001). Real-time monitoring of zinc phosphating process by quartz crystal impedance system. Thin Solid Films, 382:1-2, 263-270.
- Zhang, J., Zhou, A., Xie, Q., Wei, W., (2000). A long path length spectroelectrochemical behavior analysis of the coabsorption system. Talanta, 52:5, 903-908.
- Wu, Y., Zhou, A., Xie, Q., Cai, Y., Yao, S., (2000). A piezoelectric quartz crystal impedance study on denaturation of herring DNA. Microchemical Journal, 65:1, 67-74.
- He, D., Zhou, A., Liu, Y., Nie, L., Yao, S., (2000). A study of the visco-elasticity of zinc phosphate coatings using a quartz crystal impedance system. Surface and Coatings Technology, 126:2-3, 225-231.
- Long, Y., Li, W., He, D., Zhou, A., Wei, W., Nie, L., Yao, S., (2000). Bulk acoustic wave sensing technique applied to dibazol assay in serum and urine. Analytical Sciences, 16:6, 615-619.
- Zhou, A., Xie, B., Xie, N., (2000). Comparison of polarization curve and electrochemical quartz crystal microbalance methods for determination of copper corrosion rate. Corrosion Science, 42:3, 469-480.
- Wu, Y., Xie, Q., Zhou, A., Zhang, Y., Nie, L., Yao, S., Mo, X., (2000). Detection and analysis of Bacillus subtilis growth with piezoelectric quartz crystal impedance based on starch hydrolysis. Analytical Biochemistry, 285:1, 50-57.
- Cai, Y., Zhou, A., Wu, Y., Xie, Q., Yao, S., (2000). Determination of amino acid based on a series piezoelectric quartz crystal sensor. Analytical Letters, 33:6, 1057-1070.
- Zhou, A., He, D., Nie, L., Yao, S., (2000). Determination of the binding parameters of drug to protein by equilibrium dialysis/piezoelectric quartz crystal sensor. Analytical Biochemistry, 282:1, 10-15.
- Zhou, A., He, D., Xie, N., Xie, Q., Nie, L., Yao, S., (2000). Electrochemical quartz crystal microbalance probing the electro-formed and electro-reduced products on a copper electrode in aqueous solutions containing NaHCO3 and Na2CO3. Electrochimica Acta, 45:24, 3943-3950.
- Zhou, A., Xie, Q., Yuan, Y., Zhang, Y., Yao, S., (2000). Evaluation of electromechanical coupling factor for a piezoelectric quartz crystal in liquid phase. Analytica Chimica Acta, 419:2, 251-254.
- Zhou, A., Zhang, J., Xie, Q., Yao, S., (2000). Impedance analysis for the investigation of the behaviors of piezoelectric quartz crystal in the liquid at harmonic resonance. Sensors and Actuators B, Chemical, 67:1-2, 68-75.
- Zhang, Y., Xie, Q., Zhou, A., Yao, S., (2000). In situ monitoring of lysozyme adsorption onto bare and cysteine- or 1- octadecanethiol- modified Au electrodes using an electrochemical quartz-crystal impedance system. Analytical Sciences, 16:8, 799-805.
- Liang, C., Peng, H., Zhou, A., Nie, L., Yao, S., (2000). Molecular imprinting polymer coated BAW bio-mimic sensor for direct determination of epinephrine. Analytica Chimica Acta, 415:1-2, 135-141.
- Zhou, A., Zhang, J., Wei, W., He, D., Yao, S., Xie, Q., (2000). Monitoring of mutagenic process with piezoelectric quartz crystal impedance analysis. Talanta, 53:3, 525-533.
- Zhou, A., Xie, Q., Zhang, Y., Nie, L., Yao, S., (2000). Piezoelectric crystal impedance analysis for investigating the changes of interfacial properties due to interaction of cobalt salt with DNA immobilized on biosensor. Analytical Sciences, 16:5, 467-472.
- Zhou, A., Xie, Q., Li, P., Nie, L., Yao, S., (2000). Piezoelectric crystal impedance analysis for investigating the modification processes of protein, cross-linker, and DNA on gold surface. Applied Surface Science, 158:1-2, 141-146.
- Zhou, A., Xie, Q., Wu, Y., Cai, Y., Nie, L., Yao, S., (2000). Study of the adsorption of glutathione on a gold electrode by using electrochemical quartz crystal impedance, electrochemical impedance spectroscopy, and cyclic voltammetry. Journal of Colloid and Interface Science, 229:1, 12-20.
- Xie, Q., Wang, J., Zhou, A., Zhang, Y., Liu, H., Xu, Z., Yuan, Y., Deng, M., Yao, S., (1999). A study of depletion layer effects on equivalent circuit parameters using an electrochemical quartz crystal impedance system. Analytical Chemistry, 71:20, 4649-4656.
- Zhou, A., Xie, N., (1999). Investigation of electrosorption of organic molecules onto gold and nickel electrodes using an electrochemical quartz crystal microbalance. Journal of Colloid and Interface Science, 220:2, 281-287.
An asterisk (*) at the end of a publication indicates that it has not been peer-reviewed.
Publications | Other
An asterisk (*) at the end of a publication indicates that it has not been peer-reviewed.