Siyuan Wang Dissertation Defense
Siyuan Wang's Doctoral Dissertation Defense will occur on Oct. 6th, 2015 at 9:00 am at ENGR 402C and everyone is welcome to attend!
Siyuan’s research is focused on engineering of polyketide biosynthetic pathways to make valuable bioactive molecules in original or heterologous hosts. A biosynthetic platform was established in E. coli for the production of a variety of health-promoting molecules. Biosynthetic enzymes from different sources can be rationally combined like Legos to make desired compounds. Also, he discovered the dutomycin biosynthetic gene cluster not only provides important genetic information for future metabolic engineering of this pathway, but also allowed the biosynthesis of a promising antibacterial analog through gene disruption.