Media
2021: Kelsey Bradshaw's Interview for KVNU's For the People
2018: Dr. V's UPR UnDisciplined Episode
2016: Dr. V's TEDxUSU Talk
Publications
(Ggraduate student in Dr. V's lab; Uundergraduate student in Dr. V's lab; +corresponding author; ‡equal contribution)
36. Paterson CG, Weatherson DG, Teeples TG, E Vargis+. Isolation of primary porcine retinal pigment epithelial cells for in vitro modeling Journal of Visualized Experiments (accepted 10/30/23)
35. Suarez D, Kjar AU, Scott B, Hillam K, Vargis E, Nielson C, Sommer E, Zhang E, Holley A, Traxler A, Hughes M, Wang Y, Firpo MA, Britt D, A Park+. Can Ganciclovir and Quercetin P-188 Ameliorate Cytomegalovirus Induced Hearing Loss? The Laryngoscope (accepted 8/8/2023)
34. Rickabaugh EU,G‡, Weatherston DU,G‡, Harris TI, Jones JA+, E Vargis+. Engineering a Biomimetic in vitro Model of Bruch’s Membrane using Hagfish Slime Intermediate Filament Proteins. ACS Biomaterials Science and Engineering 9: (8), 5051-5061, 2023
33. Paterson CG, Cannon JU, E Vargis+. The Impact of Early RPE Cell Junction Loss on VEGF, Ang-2, and TIMP Secretion in Vitro. Molecular Vision 29: 87-101, 2023
32. Kjar AU, Wadsworth I, Vargis E+, D Britt+. Poloxamer 188- quercetin amplifies in vitro ganciclovir antiviral activity against cytomegalovirus. Antiviral Research 204: 105362, 2022
31. Potter M, Hanson C, Anderson AJ, Vargis E+, DW Britt+. Abiotic stressors impact outer membrane vesicle composition in a beneficial rhizobacterium: Raman spectroscopy characterization. Scientific Reports 10(1): 1-14, 2020 html
30. Clegg MHG, Harris TI, Zhang X, Barney JTU, Jones JA+, E Vargis+. Silkworm Silk Fiber Bundles as Improved In Vitro Scaffolds for Skeletal Muscle. ACS Biomaterials Science and Engineering 6(12): 6853-6863, 2020 html
29. Farjood FG, Ahmadpour A, Ostvar S, E Vargis+. Acute mechanical stress in primary porcine RPE cells induces angiogenic factor expression and in vitro angiogenesis. Journal of Biological Engineering 15: (10), 1-9, 2020 html
28. Hanson CG, Bishop MMU, Barney JTU, E Vargis+. Effect of growth media and phase on Raman spectra and discrimination of mycobacteria. Journal of Biophotonics 12: 11, e201900150, 2019 html
27. Harris T, Paterson CU, Farjood FG, Wadsworth IU, Caldwell LG, Lewis R, Jones J+, E Vargis+. Utilizing Recombinant Spider Silk Proteins to Develop a Synthetic Bruch’s Membrane for Modeling the Retinal Pigment Epithelium. ACS Biomaterials Science & Engineering 5: (8), 4023-4029, 2019 html
26. Hanson CG, Barney JTU, Bishop MMU, E Vargis+. Simultaneous isolation and label-free identification of bacteria using cDEP and Raman spectroscopy. Electrophoresis: Dielectrophoresis Special Issue 40: 1446-1456, 2019 html
Invited Submission
25. Harding CPG and E Vargis+. An in vitro microgravity model for inducing key in vivo muscle atrophy markers. BioMed Research International Article ID 2042808, 12 pages, doi.org/10.1155/2019/2042808, 2019 html
24. Farjood FG and E Vargis+. Novel Devices for Studying Acute and Chronic Mechanical Stress in Retinal Pigment Epithelial Cells. Lab on a Chip 18: 3413-3424, 2019 html
HOT article based on high scores received at peer review
23. O’Brien CM,‡ Vargis E,‡ Rudin A, Slaughter JC, Herington JL, Newton JM, Reese J, Bennett KA, A Mahadevan Jansen+. In vivo Raman spectroscopy for biochemical monitoring of the cervix throughout pregnancy. American Journal of Obstetrics & Gynecology 218: (5) 528.e1-528.e18, 2018 html
22. Bani-Baker Q, Podgorski GJ, Vargis E, NS Flann+. A Computational Study of VEGF Production by Patterned Retinal Epithelial Cell Colonies as a Model for Neovascular Macular Degeneration. Journal of Biological Engineering 11: (1), 26, 2017 html
21. Farjood FG and E. Vargis+. Physical Disruption of Cell-Cell Contact Induces VEGF Expression in RPE Cells. Molecular Vision 23: 431-446, 2017 html
20. Davis D, Doloman A, Podgorski GJ, Vargis E, NS Flann+. Exploiting Self-Organization in Bioengineered Systems: A Computational Approach. Frontiers in Bioengineering and Biotechnology 5: (27), 2017 html
19. Hanson CG and E Vargis+. Alternative cDEP Design to Facilitate Cell Isolation for Identification by Raman Spectroscopy. Sensors, 17: (2), 327 doi:10.3390/s17020327, 2017 html
Invited Submission
18. Hanson CG, Sieverts MU, E Vargis+. Effect of PCA centering and scaling on classification of mycobacteria from Raman spectra. Applied Spectroscopy, 71: (6), 1249-1255, 2016 pdf
17. Hanson CG, Israelsen NDG, Sieverts MU, E Vargis+. Fabricating a UV-Vis and Raman spectroscopy immunoassay platform. Journal of Visualized Experiments, 117: e54795, 2016 html
16. Fronk AG and E Vargis+. Methods for Culturing Retinal Pigment Epithelial Cells: a Review of Current Protocols and Future Recommendations. Journal of Tissue Engineering, 7: 1-23, 2016 html
15. Israelsen NDG, Wooley DU, Hanson CG, E Vargis+. Rational Design of a Surface-Enhanced Raman Scattering Immunoassay for Detecting Biomarkers on a Polystyrene Substrate. Journal of Biological Engineering, 10: (2), 2016 html
One of the top three most influential articles from JBE in 2015
14. Li Q, Lifu X, Harihar S, Welch DR, Vargis E, A Zhou+. In vitro Biophysical, Microspectroscopic and Cytotoxic Evaluation of Metastatic and Non-metastatic Cancer Cells in Response to Anti-cancer Drug. Analytical Methods 7: 10162-10169, 2015 link
Conference Proceeding: Baker QB, Podgorski GJ, Johnson CD, Vargis E, NS Flann+. Bridging the Multiscale Gap: Identifying Cellular Parameters from Multicellular Data. IEEE Computational Intelligence in Bioinformatics and Computational Biology (CIBCB), 2015 pdf
Magazine article: Hanson CG and E Vargis+. Microscopy and Raman Imaging: Open-system Raman Microscopy. Laser Focus World, 2015 html
13. Israelsen NDG‡, Hanson CG‡, E Vargis+. Nanoparticle Properties and Synthesis Effects on Surface-Enhanced Raman Scattering (SERS) Enhancement Factor: an Introduction. The Scientific World Journal 2015: Article ID 124582, 12 pages, 2015 html
12. O’Brien CM‡, Vargis E‡, Paria BC, Bennett KA, Mahadevan-Jansen A, J Reese+. Raman Spectroscopy Provides a Noninvasive Approach for Determining Biochemical Composition of the Pregnant Cervix In Vivo. Acta Paediatrica, 103: (7), 715-721, 2014 pdf
11. Vargis E, Peterson CB, Morrell-Falvey J, Retterer ST+, CP Collier+. The Effect of Retinal Pigment Epithelial Cell Patch Size on Growth Factor Expression. Biomaterials, 35: (13), 3999-4004, 2014 pdf
10. Pence IJ, Vargis E, A Mahadevan-Jansen+. Assessing Variability of In Vivo Tissue Raman Spectra. Applied Spectroscopy, 67: (7), 789-800, 2013 html
9. Vargis E, Brown N, Williams KC, Paria BC, Al-Hendy A, Reese J, A Mahadevan-Jansen+. Detecting Biochemical Changes that Occur in the Rodent Cervix during Pregnancy using Raman Spectroscopy. Annals of Biomedical Engineering, 40: (8), 1814-1824, 2012 html
8. Vargis E, Tang Y-W, Khabele D, A Mahadevan-Jansen+. Near-Infrared Raman Microspectroscopy Detects High-Risk Human Papillomaviruses. Translational Oncology, 5: (3), 172-179, 2012 pdf
7. Vargis E, Byrd T, Logan Q, Khabele D, A Mahadevan-Jansen+. Sensitivity of Raman Spectroscopy to Normal Patient Variability. Journal of Biomedical Optics, 16: (11), 117004-1-9, 2011 html
6. Keller MD, Vargis E, Granja ND, Robert TH, Mycek MA, Kelley MC, A Mahadevan-Jansen+. Development of a Spatially Offset Raman Spectroscopy Probe for Breast Tumor Surgical Margin Evaluation. Journal of Biomedical Optics, 16: (7), 077006-1-8, 2011 pdf
5. Vargis E, Kanter EM, Majumder S, Keller MD, Beaven RB, Rao GG, A Mahadevan-Jansen+. Effect of Normal Variations on Classification of Raman Spectra of Cervical Tissue. Analyst, 136: (14), 2981-2987, 2011 pdf
4. Perez JW, Vargis E, Russ PK, Haselton FR, DW Wright+. Detection of Respiratory Syncytial Virus Using Nanoparticle Amplified Immuno-PCR. Analytical Biochemistry, 410: (1), 141-148, 2011 pdf
3. Kanter EM, Vargis E, Majumder S, Keller MD, Beaven RB, Rao GG, A Mahadevan-Jansen+. Application of Raman spectroscopy for Cervical Dysplasia Diagnosis. Journal of Biophotonics, 2: (1-2), 81-90, 2009 pdf
2. Kanter EM, Majumder S, Vargis E, Robichaux-Viehoever A, Kanter G, Shappell H, III Jones H, A Mahadevan-Jansen+. Multiclass Discrimination of Cervical Precancers using Raman Spectroscopy. Journal of Raman Spectroscopy, 40: (2), 205-211, 2009 pdf
1. Shyamala G+, Chou Y-C, Cardiff RD, E Vargis. Effect of c-neu/ErbB2 Expression Levels on Estrogen Receptor alpha-Dependent Proliferation in Mammary Epithelial Cells: Implication for Breast Cancer Biology. Cancer Research, 66: (21), 10391-10398, 2006 pdf
Conference Podium Talks (since joining USU)
Farjood FG and E Vargis. Isolation Affects VEGF Expression in Retinal Pigment Epithelial Cells. Institute of Biological Engineering. April 2016
Hanson CG and E Vargis. The Use of Microfluidics and Dielectrophoresis for Separation, Concentration, and Identification of Bacteria. SPIE Photonics West: Microfluidics, BioMEMS, and Medical Microsystems XIV. February 2016
Israelsen NDG and E Vargis. Raman Microscope System for the Detection of B-cell Malignancies using Surface-Enhanced Raman Scattering. Biophotonic Imaging for Medicine: A Digital Conference. June 2015
Gertsch S, Bedingfield SU, Lawanto SU, and E Vargis. Targeted Drug Delivery System for Kidney and/or Liver Failure Patients using Human Serum Albumin. National Conference on Undergraduate Research. April 2015
Israelsen NDG and E Vargis. Surface-enhanced Raman Spectroscopy Based Detection of Leukemia Cell Surface Markers. SciX 2014 Conference Presented by FACSS. September 2014
Hanson CHG and E Vargis. Application of SERS Magnetic Nanoparticles to Concentrate, Detect, and Identify Mycobacteria. SciX 2014 Conference Presented by FACSS. September 2014
O’Brien CM, Vargis E, Reese J, Bennett K, A Mahadevan-Jansen. In Vivo Raman Spectroscopy as a Clinical Tool to Detect Biomedical Changes in the Pregnant Cervix. SPIE Photonics West. January 2014
Hanson CHG and E Vargis. A Simple Method for Bacterial Concentration, Detection and Identification Using SERS Magnetic Nanoparticles. USU’s Graduate Research Symposium. April 2014
Vargis E. Development of Tissue Models and Spectroscopy Disease Detection Platforms for Biomedical Applications. nanoUtah. October 2013